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Preparation of 14 C‐Labelled Vincristine and N‐Desmethyl‐N‐formyl‐leurosine
Author(s) -
Zóyomi Gábor,
Jovánovics Karola,
Dancsi Lajos
Publication year - 1977
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580130412
Subject(s) - desmethyl , chemistry , formylation , formic acid , radiochemistry , organic chemistry , catalysis , metabolite , biochemistry
14 C‐Labelled vincristine was prepared from N‐desmethyl vinblastine by formylation with 14 C‐formic acid. Excess radioactive formic acid was recovered as sodium formate. 14 C‐Labelled N‐desmethyl‐N‐formyl‐leurosine was prepared analogously.