Strategy for  14 C‐labeling of a series of bis(heteroaryl)piperazines | Zendy

Arjomandi Omid Khalili | Zendy; Saemian Nader | Zendy; Shirvani Gholamhossein | Zendy; Javaheri Mohsen | Zendy; Esmailli Kameh | Zendy

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Strategy for 14 C‐labeling of a series of bis(heteroaryl)piperazines

Author(s) -

Arjomandi Omid Khalili,

Saemian Nader,

Shirvani Gholamhossein,

Javaheri Mohsen,

Esmailli Kameh

Publication year - 2011

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.1880

Subject(s) - chemistry , potassium thiocyanate , moiety , imidazole , hydroxymethyl , stereochemistry , thiocyanate , sequence (biology) , piperazine , combinatorial chemistry , organic chemistry , biochemistry

Four bis(heteroaryl)piperazines labeled with carbon‐14 in the 2‐position of imidazole moiety were prepared as part of a 4‐step (or 5‐step) sequence from 5‐hydroxymethyl‐2‐mercapto‐1‐benzylimida‐zole‐[2‐ 14 C] as a key synthetic intermediate which has been synthesized from potassium [ 14 C]‐thiocyanate. Copyright © 2011 John Wiley & Sons, Ltd.

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