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Synthesis of deuterium‐labelled trantinterol
Author(s) -
Wen Hongliang,
Pan Li,
Zhang Yingdan,
Ma Jiacheng,
Qin Liqiong,
Cheng Maosheng
Publication year - 2010
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1796
Subject(s) - chemistry , deuterium , agonist , radiochemistry , pharmacology , biochemistry , nuclear physics , receptor , physics , medicine
Trantinterol, a selective β 2 ‐adrenoceptor agonist, is currently in Phase II clinical trials for the treatment of asthma and bronchitis. The synthesis of deuterium‐labelled trantinterol is described. The labelled trantinterol is used as an internal standard for the analysis and metabolic studies. Copyright © 2010 John Wiley & Sons, Ltd.

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