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Synthesis of N ‐methylmorpholine N ‐( 17 O‐oxide) and N ‐methylmorpholine 15 N ‐( 17 O‐oxide)
Author(s) -
Opietnik Martina,
Potthast Antje,
Kitaoka Takuya,
Rosenau Thomas
Publication year - 2010
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1708
Subject(s) - chemistry , hydrogen peroxide , oxide , electrolysis , inorganic chemistry , nuclear chemistry , organic chemistry , electrolyte , electrode
N ‐Methylmorpholine N ‐( 17 O‐oxide) and N ‐methylmorpholine 15 N ‐( 17 O‐oxide) were prepared from N ‐methylmorpholine and 15 N ‐methylmorpholine by oxidation with H 2 17 O 2 . The facile one‐pot procedure provided yields of 82 and 76%, respectively. The labeled hydrogen peroxide was obtained by electrolysis of H 2 17 O followed by autoxidation of 2‐ethylanthraquinol with the molecular oxygen 17 O 2 generated. The compounds serve for mechanistic studies into gold nanoparticle generation in NMMO solution. Copyright © 2009 John Wiley & Sons, Ltd.