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Radiosynthesis of [ 3 H]‐ABP688 using [ 3 H]‐methyl nosylate: a non‐volatile alternative methylating agent
Author(s) -
Li Pixu,
Olszewski John D.
Publication year - 2009
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1665
Subject(s) - radiosynthesis , chemistry , yield (engineering) , desmethyl , radiochemistry , organic chemistry , in vivo , biochemistry , materials science , microbiology and biotechnology , metabolite , metallurgy , biology
Tritiated ABP688 was synthesized from desmethyl ABP688 with [ 3 H]‐methyl nosylate in high radiochemical yield. The results demonstrate that [ 3 H]‐methyl nosylate is a good alternative methylating agent for radiosynthesis. Copyright © 2009 John Wiley & Sons, Ltd.