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Synthesis of a series of carbon‐14 labelled 4‐aminoquinazolines and quinazolin‐4 (3H)‐ones
Author(s) -
Saemian Nader,
Arjomandi Omid Khalili,
Shirvani Gholamhossein
Publication year - 2009
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1658
Subject(s) - chemistry , benzamide , carbon 14 , carbon fibers , stereochemistry , organic chemistry , medicinal chemistry , physics , materials science , quantum mechanics , composite number , composite material
Abstract 4‐Aminoquinazolines and quinazolin‐4 (3H)‐ones, both labelled with carbon‐14 in the 4‐position, were prepared from 2‐aminobenzonitrile‐[cyano‐ 14 C] and 2‐aminobenzoic acid‐[carboxy ‐ 14 C] or 2‐amino‐ benzamide‐[carboxy ‐ 14 C], respectively, using rapid, one‐pot procedures under microwave enhanced conditions. Copyright © 2009 John Wiley & Sons, Ltd.