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The effect of adding Crabtree's catalyst to rhodium black in direct hydrogen isotope exchange reactions
Author(s) -
Schou Søren Christian
Publication year - 2009
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1612
Subject(s) - chemistry , rhodium , catalysis , deuterium , hydrogen isotope , hydrogen , hydrogen–deuterium exchange , kinetic isotope effect , organic chemistry , physics , quantum mechanics
A new catalytic system based on rhodium black using Crabtree's catalyst as an additive for direct hydrogen isotope exchange in aromatic compounds has been investigated. The level of deuterium incorporation can be improved from for example 16 to 93%. The new catalyst mixture tolerates a variety of solvents. Copyright © 2009 John Wiley & Sons, Ltd.