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Synthesis of [ 14 C]‐, [ 13 C 4 ]‐, and [ 13 C 4 , 15 N 2 ]‐ 5‐amino‐4‐iodopyrimidine
Author(s) -
Latli Bachir,
Jones PaulJames,
Krishnamurthy Dhileepkumar,
Senanayake Chris H.
Publication year - 2008
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1477
Subject(s) - chemistry , carbon 13 , carbon 14 , carbon fibers , formamide , nitrogen , isotopes of carbon , compounds of carbon , isotope , radiochemistry , isotopes of nitrogen , chemical reaction , organic chemistry , nuclear physics , physics , total organic carbon , materials science , composite number , composite material
5‐Amino‐4‐iodopyrimidine labeled with either carbon‐14 or with the stable isotopes carbon‐13 and nitrogen‐15 was prepared starting from commercially available labeled diethylmalonate and formamide. This compound is a useful intermediate for carbon–nitrogen and carbon–carbon bond formations. Copyright © 2008 John Wiley & Sons, Ltd