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Synthesis of deuterium‐labelled etorphine and dihydroetorphine
Author(s) -
Chen YiJing,
Chen Chinpiao
Publication year - 2007
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1397
Subject(s) - chemistry , etorphine , deuterium , mass spectrometry , chromatography , codeine , radiochemistry , gas chromatography , opioid , pharmacology , biochemistry , morphine , nuclear physics , medicine , (+) naloxone , physics , receptor
The synthesis of deuterium‐labelled [ 2 H 6 ]‐etorphine and [ 2 H 6 ]‐dihydroetorphine from codeine is described. The isotopically labelled compounds are used as internal standards in gas chromatography–mass spectrometry (GC–MS) assays. Copyright © 2007 John Wiley & Sons, Ltd.