Premium
Imaging the proliferative status of tumors with PET
Author(s) -
Mach Robert H.,
Wheeler Kenneth T.
Publication year - 2007
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1269
Subject(s) - positron emission tomography , chemistry , biomarker , pet imaging , cancer research , molecular imaging , imaging biomarker , brain positron emission tomography , nuclear medicine , preclinical imaging , computational biology , medical physics , biochemistry , in vivo , magnetic resonance imaging , radiology , medicine , genetics , biology
The development of radiotracers for imaging solid tumors has recently focused on measuring a tumor's proliferative status. Two different strategies have emerged: (1) radiolabeled DNA precursors that measure DNA synthesis; and (2) radiotracers that label the sigma‐2 receptor, a putative biomarker of proliferation. This paper provides a brief description of these two different methods of imaging tumor proliferation that are currently being developed in the field of positron emission tomography (PET). Copyright © 2007 John Wiley & Sons, Ltd.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom