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Convenient and efficient tritiation of aristolochic acid I (AAI) and aristolochic acid II (AAII) with tritiated water
Author(s) -
Ray Tapan,
Wu Amy,
Allentoff Alban J.
Publication year - 2007
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1178
Subject(s) - tritiated water , chemistry , tritium , radiochemistry , organic chemistry , nuclear physics , physics
Iridium‐catalysed isotope exchange with tritiated water is an efficient way to introduce tritium into polar molecules. The method is feasible for compounds containing a nitro group.It has been confirmed through our experiment that using excess tritiated water, the H/T exchange can be quantitative. Copyright © 2007 John Wiley & Sons, Ltd.