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An efficient laboratory synthesis of α‐deuteriated profens
Author(s) -
Coumbarides Gregory S.,
Dingjan Marco,
Eames Jason,
Flinn Anthony,
Northen Julian
Publication year - 2006
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1105
Subject(s) - chemistry , deuterium , combinatorial chemistry , organic chemistry , nuclear physics , physics
An efficient and practical laboratory synthesis of a series of 2‐deuterio‐2‐arylpropionic acids (α‐deuterioprofens) is described. The levels of deuterium incorporation are high and the products are synthetically useful. Copyright © 2006 John Wiley & Sons, Ltd.

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