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An improvement to the synthesis of deuterated meso‐tetraphenylporphyrins
Author(s) -
Asano Motoko S.,
Abe Hiroshi,
Kaizu Youkoh
Publication year - 2006
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1077
Subject(s) - chemistry , deuterium , porphyrin , pyrrole , labelling , chemical synthesis , relaxation (psychology) , photochemistry , combinatorial chemistry , organic chemistry , biochemistry , physics , quantum mechanics , in vitro , psychology , social psychology
An improved method for the synthesis of deuterated tetraphenylporphyrins (TPPs) is reported. In this method, deuterium labelling at the pyrrole– β ‐position is increased to more than 95 at%. TPP is the most widely used synthetic porphyrin and high deuterium incorporation is essential for spectroscopic studies and kinetic studies involving relaxation processes. Copyright © 2006 John Wiley & Sons, Ltd.