Synthesis of d 3 ‐cerivastatin for use as internal standard in a LC/MS/MS method developed for quantitation of the drug in human serum | Zendy

Chen BangChi | Zendy; Bednarz Mark S. | Zendy; Zhang Huiping | Zendy; Guo Peng | Zendy; Jemal Mohammed | Zendy; Robl Jeffrey A. | Zendy; Biller Scott A. | Zendy; Sundeen Joseph E. | Zendy; Balasubramanian Balu | Zendy; Barrish Joel C. | Zendy

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Synthesis of d 3 ‐cerivastatin for use as internal standard in a LC/MS/MS method developed for quantitation of the drug in human serum

Author(s) -

Chen BangChi,

Bednarz Mark S.,

Zhang Huiping,

Guo Peng,

Jemal Mohammed,

Robl Jeffrey A.,

Biller Scott A.,

Sundeen Joseph E.,

Balasubramanian Balu,

Barrish Joel C.

Publication year - 2006

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.1050

Subject(s) - cerivastatin , chemistry , chromatography , drug , human plasma , combinatorial chemistry , pharmacology , biochemistry , enzyme , medicine , reductase

d 3 ‐Cerivastatin was synthesized as an internal standard for use in a LC/MS/MS method developed for the simultaneous quantitative determination of the drug in human serum. d 3 ‐Cerivastatin was efficiently prepared on large scale from d 3 ‐iodomethane using improved procedures. Copyright © 2006 John Wiley & Sons, Ltd.

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