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A rapid microwave assisted synthesis of [U‐ 14 C]isosorbide and dimethyl[U‐ 14 C]isosorbide from D ‐[U‐ 14 C]glucose
Author(s) -
Mathew K. M.,
Ravi S.,
Padmanabhan D.,
Unny V. K. P.,
Sivaprasad N.
Publication year - 2006
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1047
Subject(s) - isosorbide , chemistry , yield (engineering) , isosorbide dinitrate , microwave , nuclear chemistry , d glucose , radiochemistry , stereochemistry , organic chemistry , medicine , physics , materials science , quantum mechanics , metallurgy
[U‐ 14 C]Isosorbide and [U‐ 14 C]dimethyl isosorbide with a specific activity of 462 MBq/mmol was prepared from D ‐[U‐ 14 C]glucose, in an overall yield of 79%, under microwave heating conditions. Copyright © 2006 John Wiley & Sons, Ltd.
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