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The no‐carrier‐added synthesis of bromine‐76 labeled alkenyl and alkynyl bromides using organotrifluoroborates
Author(s) -
Kabalka George W.,
Mereddy Arjun R.,
Green James F.
Publication year - 2006
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.1025
Subject(s) - chemistry , bromine , halogenation , organic chemistry , combinatorial chemistry
A straightforward radiobromination procedure has been developed for the construction of radiobrominated alkenyl and alkynyl bromides. The organotrifluoroborates used as the reactive intermediates are unique in that they are quite polar and thus readily separated from the desired products. Copyright © 2005 John Wiley & Sons, Ltd.