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Dendritic cell maturation is required for initiation of the immune response
Author(s) -
Rescigno Maria,
Winzler Claudia,
Delia Domenico,
Mutini Carmela,
Lutz Manfred,
RicciardiCastagnoli Paola
Publication year - 1997
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1002/jlb.61.4.415
Subject(s) - biology , immune system , antigen , antigen presenting cell , dendritic cell , microbiology and biotechnology , antigen presentation , immunology , function (biology) , follicular dendritic cells , lymphatic system , t cell , process (computing) , computer science , operating system
Dendritic cells (DC) are professional antigen‐presenting cells (APC) whose primary function is to capture, process, and present antigens to unprimed T cells [1, 2]. They comprise a system of leukocytes widely distributed in all tissues, especially in those that provide an environmental interface (skin and mucosal surfaces) and in lymphoid organs [1].