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Kinky integrins reveal a new wrinkle in neutrophil activation
Author(s) -
Morikis Vasilios A,
Rivara Kathryn,
Simon Scott I
Publication year - 2020
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1002/jlb.3ce1019-273r
Subject(s) - integrin , mechanotransduction , biology , microbiology and biotechnology , blocking (statistics) , transmembrane protein , wrinkle , biophysics , immunology , receptor , biochemistry , genetics , computer science , computer network
Discussion on the flexible kink produced in the β 2 ‐integrin transmembrane domain blocking mechanotransduction of signals necessary for neutrophil arrest and spreading.