Premium
Synthesis of rac ‐Bisabola‐3(15),10‐dien‐7‐ol
Author(s) -
Weyerstahl Peter,
Schlicht Volker
Publication year - 1997
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199719970824
Subject(s) - chemistry , grignard reaction , odor , medicinal chemistry , stereochemistry , organic chemistry , reagent
1‐Acetyl‐4‐methylenecyclohexane ( 6 ) was obtained from ethyl 4‐methylenecyclohexane carboxylate ( 2 ), by DIBAH reduction (→ 4 ), Grignard reaction (→ 5 ) and oxidation. A further Grignard reaction furnished the rac ‐bisabola‐3(15),10‐dien‐7‐ol ( 1 ), which we isolated recently from Vetiver oil. Its odor is mainly aldehydic (fatty, floral).