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Derivatives of Natural Tetrapyrroles for Photodynamic Therapy, 4 . Oxidative Degradation Studies: Direct Analysis and Determination of Ether and Ester Linkages in Porphyrin Dimers and Oligomers of Hematoporphyrin Derivative (HPD),
Author(s) -
Risch Nikolaus,
Hesse Ulrike,
Josephs Andrea,
Gauler Rainer
Publication year - 1996
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199619961122
Subject(s) - hematoporphyrin , chemistry , porphyrin , ether , derivative (finance) , degradation (telecommunications) , diphenyl ether , oxidative phosphorylation , photodynamic therapy , combinatorial chemistry , photochemistry , organic chemistry , biochemistry , telecommunications , computer science , financial economics , economics
Oxidative degradation studies of dimeric porphyrins provide valuable information about the individual linkages between the porphyrin units. MS and NMR data of the degradation products of hematoporphyrin derivative furnish unambiguous evidence of ester and ether linkages in the di‐ and oligomeric compounds of HPD.