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Synthesis, Resolution and Crystal Structure of a New Optically Active Nitroxide Radical
Author(s) -
Benfaremo Nicholas,
Steenbock Marco,
Klapper Markus,
Müllen Klaus,
Enkelmann Volker,
Cabrera Karin
Publication year - 1996
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199619960912
Subject(s) - nitroxide mediated radical polymerization , chemistry , enantiomer , resolution (logic) , optically active , crystal structure , stereochemistry , crystallography , organic chemistry , radical polymerization , polymer , artificial intelligence , computer science , copolymer
The synthesis of the readily available racemate of the nitroxide radical 5 is described. The product exhibits exclusively the trans configuration. The cis product was not obtained. Optically pure enantiomers of 5 were isolated in gram quantities by chiral HPLC. Thus, separation of the enantiomers of a nitroxide radical was achieved for the first time. The structure of 5 was proven by a single‐crystal diffraction study.