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Terminally Protected 1‐Phenyl‐1,5‐hexadiyne‐3,4‐diones as First Members of the Class of Dialkynyl‐1,2‐diones
Author(s) -
Faust Rüdiger,
Weber Christian
Publication year - 1996
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199619960803
Subject(s) - chemistry , benzotriazole , hydrolysis , alkoxy group , medicinal chemistry , organic chemistry , stereochemistry , alkyl
Reaction of lithiated 1‐(1‐ethoxy‐3‐phenyl‐prop‐2‐ynyl)‐1 H ‐benzotriazole ( 3 ) with various acetylenic aldehydes followed by periodinane oxidation and hydrolysis yields terminally protected 1‐phenyl‐1,5‐hexadiyne‐3,4‐diones 7a–d as the first examples of dialkynyl‐1,2‐diones.