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New Compounds from 6,7‐Dihydrobenzo[ c ]thiophen‐4(5 H )‐ones.
Author(s) -
Prim Damien,
Joseph Delphine,
Kirsch Gilbert
Publication year - 1996
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199619960214
Subject(s) - moiety , chemistry , reactivity (psychology) , thiophene , ketone , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , medicine , alternative medicine , pathology
The reactivity of the ketone moiety in 6,7‐dihydrobenzo[c]‐thiophen‐4(5 H )‐ones 1 was used to generate new benzo[ c ]‐thiophene derivatives. The behaviour of the ketones under Vilsmeier‐Haack‐Arnold conditions was studied. Generally, the reactivity of the ketone moiety is shown to be dependent on the substituents of the thiophene ring.