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Antibiotics from Gliding Bacteria, LXXIII Indole and Quinoline Derivatives as Metabolites of Tryptophan in Myxobacteria
Author(s) -
Böhlendorf Bettina,
Bedorf Norbert,
Jansen Rolf,
TrowitzschKienast Wolfram,
Höfle Gerhard,
Forche Edgar,
Gerth Klaus,
Irschik Herbert,
Kunze Brigitte,
Reichenbach Hans
Publication year - 1996
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199619960108
Subject(s) - myxobacteria , indole test , chemistry , quinoline , tryptophan , antibiotics , bacteria , microbiology and biotechnology , biochemistry , organic chemistry , biology , amino acid , genetics
Two groups of 3‐substituted indole 1, 6–9 as well as 4‐substituted quinoline derivatives 2–5 and harman ( 10 ) were isolated from various species and genera of myxobacteria. They were identified by their spectroscopic data. Some of the metabolites show moderate antifungal activity. Their biosynthetic origin in myxobacteria was demonstrated for 1, 2 , and 3 by incorporation of L ‐[1'‐ 14 C]tryptophan.