Stereoselective synthesis of oligo(tetrahydrofurans): Linear and convergent routes to bi‐ and tertetrahydrofurans | Zendy

Koert Ulrich | Zendy; Stein Matthias | Zendy; Wagner Holger | Zendy

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Stereoselective synthesis of oligo(tetrahydrofurans): Linear and convergent routes to bi‐ and tertetrahydrofurans

Author(s) -

Koert Ulrich,

Stein Matthias,

Wagner Holger

Publication year - 1995

Publication title -

liebigs annalen

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 0947-3440

DOI - 10.1002/jlac.1995199508192

Subject(s) - chemistry , stereoselectivity , annonaceae , stereochemistry , convergent synthesis , combinatorial chemistry , organic chemistry , botany , biology , catalysis

The „dimeric” and „trimeric” oligo(tetrahydrofurans) (oligo‐THFs) 24, 28, 32 , and 38 were synthesized stereoselectively according to a linear and a convergent synthetic strategy. The oligo‐THFs thus obtained are important intermediates for the synthesis of artificial ion channels. Furthermore, they can be used in the total synthesis of Annonaceae acetogenins, a class of natural occurring oligo‐THFs with promising pharmacological properties.

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