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Premium Synthesis of substituted chiral piperazinones as building blocks for peptidomimetics
Kolter Thomas,
Dahl Christina,
Giannis Athanassios
Publication year1995
Publication title
liebigs annalen
Resource typeJournals
PublisherWILEY‐VCH Verlag
Abstract A new approach to 3,6‐disubstituted chiral piperazinones 6a, b and 7a, b from D‐glucosamine hydrochloride ( 1 ) or N ‐Z‐ D ‐glucosamine ( 8 ) and L‐amino acid derivatives 2a, b or 9a, b is presented. Both final products and the intermediate pseudopeptides constitute valuable starting materials for the synthesis of peptidomimetics.
Subject(s)amino acid , biochemistry , chemistry , combinatorial chemistry , d glucosamine , glucosamine , hydrochloride , organic chemistry , peptide , peptidomimetic , stereochemistry
SCImago Journal Rank0.825

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