z-logo
Premium
Synthesis of substituted chiral piperazinones as building blocks for peptidomimetics
Author(s) -
Kolter Thomas,
Dahl Christina,
Giannis Athanassios
Publication year - 1995
Publication title -
liebigs annalen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0947-3440
DOI - 10.1002/jlac.199519950487
Subject(s) - peptidomimetic , chemistry , d glucosamine , glucosamine , hydrochloride , combinatorial chemistry , amino acid , stereochemistry , organic chemistry , peptide , biochemistry
Abstract A new approach to 3,6‐disubstituted chiral piperazinones 6a, b and 7a, b from D‐glucosamine hydrochloride ( 1 ) or N ‐Z‐ D ‐glucosamine ( 8 ) and L‐amino acid derivatives 2a, b or 9a, b is presented. Both final products and the intermediate pseudopeptides constitute valuable starting materials for the synthesis of peptidomimetics.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here