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Selektive Synthese ortho ‐disubstituierter Tetrahydroanthracene mit Retinoidstruktur
Author(s) -
Hanefeld Wolfgang,
Jung Manfred
Publication year - 1994
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199419940404
Subject(s) - chemistry , palladium , substitution (logic) , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , catalysis , computer science , programming language
Selective Synthesis of ortho ‐Disubstituted Tetrahydroanthracenes with Retinoid Structure A synthesis of analogues of Temarotene (Ro 15‐0778) ( 1 ) is described. This synthesis achieves the selective substitution in ortho ‐positions of a tetrahydroanthracene system using palladium‐catalyzed coupling techniques.