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Cholesteno‐Indole, I – Synthese von 1′ H ‐5α‐Cholest‐2‐eno[3,2‐ b ]indolen
Author(s) -
Samu János,
Botyánszki János,
Duddeck Helmut,
Snatzke Günther
Publication year - 1993
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1993199301198
Subject(s) - indole test , chemistry , stereochemistry
Cholesteno Indoles, I. – Preparation of 1′ H ‐5α‐Cholest‐2‐eno[3,2‐ b ]indoles 1′ H ‐5α‐Cholest‐2‐eno[3,2‐ b ]indole ( 1a ), the corresponding N ‐methyl, N ‐acetyl, and N ‐formyl compounds 1b – d , as well as the respective methoxy derivatives 2b–5d have been synthesized as model compounds for intended CD investigations. Application of the Fischer indole synthesis afforded the compouds 1a–5a which were N ‐methylated to 1b–5b , N ‐acetylated to 1c–5c , and N ‐formylated to 1d–5d .