Premium
Facile and General Synthesis of 2‐, 3‐, or 4‐[(Dialkylamino)alkyl]pyridines and ‐piperidines
Author(s) -
Cohen Victor I.,
Jin Biyun,
Reba Richard C.
Publication year - 1993
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1993199301127
Subject(s) - chemistry , alkyl , pyridine , catalysis , chloride , organic chemistry , medicinal chemistry , combinatorial chemistry
Reaction of (dialkylamino)alkyl chloride with picolyllithiums provides the corresponding pyridine derivatives from which the piperidines are obtained by catalytic hydrogenation.