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Präparative Enantiomerentrennung einer Chroman‐2‐carbonsäure durch Chromatographie von Glucose‐Derivaten
Author(s) -
Netscher Thomas,
Gautschi Iwan
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199219920194
Subject(s) - chemistry , saponification , reagent , chromatography , enantiomer , organic chemistry , supercritical fluid chromatography , gas chromatography , ether
Preparative Separation of the Enantiomers of a Chroman‐2‐carboxylic Acid via Chromatography of Glucose Derivatives Starting from the commercially available racemic carboxylic acid 2a , b ( S )‐Trolox methyl ether ( 1a ), useful as a chiral reagent for capillary gas chromatography and supercritical fluid chromatography, was obtained in enantiomerically pure form (e.e. >99.9%) by the separation of esters derived from diacetone D ‐glucose and subsequent saponification.