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Thiazol‐ und Thiazolidin‐Derivate aus Benzoylthioharnstoffen
Author(s) -
Wobig Dieter
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199219920175
Subject(s) - chemistry , medicinal chemistry , combinatorial chemistry
Derivatives of Thiazoles and Thiazolidines from Benzoylthioureas The thioureas 1a – c react with the derivatives of γ‐bromocrotonic acid 2a and 2b to give the thiazoles 3a – f . Contrary to this, the treatment of 1d or 1e with 4 or 2a and 2b leads to the thiazolidines 5a and 5b or 6a – d , respectively. 3g can be synthesized by the reaction of N ‐benzimidoyl‐ N′ ‐phenylthiourea ( 7 ) with 2a .