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Synthese linearer und verzweigter perfluoralkylierter Carbonsäuren durch radikalische Addition von Perfluoralkyliodiden an ungesättigte Fettsäuren
Author(s) -
Metzger Jürgen O.,
Linker Ursula
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199219920139
Subject(s) - chemistry , regioselectivity , organic chemistry , base (topology) , chloride , medicinal chemistry , catalysis , mathematical analysis , mathematics
Synthesis of Linear and Branched Perfluoroalkylated Carboxylic Acids by Radical Addition of Perfluoroalkyl Iodides to Unsaturated Fatty Acids Linear and branched perfluoroalkylated carboxylic acids, i.e. 6a , 11a , 12a , 15a and 16a , are easily available by tin(II) chloride/silver(I) acetate‐initiated free radical additions of perfluoroalkyl iodides to unsaturated carboxylic acids 1a – 3a followed by tributylstannan reduction of the respective addition products. The unsaturated perfluoroalkylated carboxylic acids 7a can be obtained by regioselective base‐catalyzed elimination of HI from the addition products.