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Base‐Mediated Ring Expansion Reactions, III. A New Route from Dihydroisoquinolines to 2‐benzazepines
Author(s) -
Groth Ulrich,
Richter Lutz,
Schöllkopf Ulrich,
Zindel Jürgen
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201193
Subject(s) - benzazepines , chemistry , ring (chemistry) , base (topology) , stereochemistry , combinatorial chemistry , organic chemistry , mathematics , mathematical analysis
The substituted 2‐benzazepines 4 , 5 and 12 were prepared by a base‐mediated ring expansion reaction of mesylates 1a – e , which were synthesized in 4 to 5 steps by starting from benzolactams 6 .
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