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Kondensierte 1,2‐Dithiole, II. Synthese von Thieno‐1,2‐dithiolen
Author(s) -
Stachel HansDietrich,
Schorp Matthias,
Zoukas Thomas
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201171
Subject(s) - chemistry , contraction (grammar) , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry , medicine
Ring‐Fused 1,2‐Dithioles, II. — Synthesis of Thieno‐1,2‐dithioles A series of thieno‐1,3‐dithiines 5 has been synthesized starting with the β‐thioxoester 4 . The dithiines undergo oxidative ring contraction to the corresponding thieno‐1,2‐dithioles 6 . Analogously, the dithiolo‐dithiines 8 form the 1,2‐dithiolo‐1,2‐dithioles (1,2,4,5‐tetrathiapentalenes) 14 by ring contraction. — The ester function of 6f is easily removed to give 2 , the thioanalog of the antibiotic thiolutine.