Premium
Kondensierte 1,2‐Dithiole, II. Synthese von Thieno‐1,2‐dithiolen
Author(s) -
Stachel HansDietrich,
Schorp Matthias,
Zoukas Thomas
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201171
Subject(s) - chemistry , contraction (grammar) , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry , medicine
Ring‐Fused 1,2‐Dithioles, II. — Synthesis of Thieno‐1,2‐dithioles A series of thieno‐1,3‐dithiines 5 has been synthesized starting with the β‐thioxoester 4 . The dithiines undergo oxidative ring contraction to the corresponding thieno‐1,2‐dithioles 6 . Analogously, the dithiolo‐dithiines 8 form the 1,2‐dithiolo‐1,2‐dithioles (1,2,4,5‐tetrathiapentalenes) 14 by ring contraction. — The ester function of 6f is easily removed to give 2 , the thioanalog of the antibiotic thiolutine.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom