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Isolation of 4‐Hydroxy‐5‐methoxycanthin‐6‐one from Picrasma quassioides and Revision of a Previously Reported Structure
Author(s) -
Liu Jian,
Davidson R. Stephen,
Heijden Robert Van Der,
Verpoorte Robert,
Howarth Oliver W.
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201162
Subject(s) - simaroubaceae , chemistry , alkaloid , stereochemistry , carbon 13 nmr , two dimensional nuclear magnetic resonance spectroscopy
A new alkaloid, 4‐hydroxy‐5‐methoxycanthin‐6‐one ( 1 ), has been isolated from Picrasma quassioides (Simaroubaceae), and its structure has been determined by high‐field 1 H‐ and 13 C‐NMR, 13 C, 1 H‐HETCOR, 1 H, 1 H‐2D‐COSY, and NOE‐difference spectra. Previous data, interpreted by other workers as being from this compound, is instead tentatively reassigned to another new alkaloid structure, 4‐hydroxy‐3‐methylcanthine‐5,6‐dione ( 2 ).