Premium
α‐Amidoalkylation of Ambident Nucleophiles by Means of N ‐Benzoylbenzaldimine
Author(s) -
Dobrev Alexander,
Benin Vladimir,
Nechev Lubomir
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201141
Subject(s) - chemistry , nucleophile , medicinal chemistry , pyrrolidinones , organic chemistry , catalysis
tert ‐Butyl esters 1a – c and N , N ‐disubstituted amides 1d – h of carboxylic acids as well as N ‐substituted pyrrolidinones 1i , j and 3‐morpholinone 1k are α‐amidoalkylated with N ‐benzoylbenzylideneamine ( 2 ). The stereochemical course of the reaction is discussed.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom