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α‐Amidoalkylation of Ambident Nucleophiles by Means of N ‐Benzoylbenzaldimine
Author(s) -
Dobrev Alexander,
Benin Vladimir,
Nechev Lubomir
Publication year - 1992
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1992199201141
Subject(s) - chemistry , nucleophile , medicinal chemistry , pyrrolidinones , organic chemistry , catalysis
tert ‐Butyl esters 1a – c and N , N ‐disubstituted amides 1d – h of carboxylic acids as well as N ‐substituted pyrrolidinones 1i , j and 3‐morpholinone 1k are α‐amidoalkylated with N ‐benzoylbenzylideneamine ( 2 ). The stereochemical course of the reaction is discussed.