Synthese von disubstituierten Cyclopropa[ c ]pyranosiden aus 2,3‐Epoxy‐4‐triflat‐pyranosiden

Synthesis of Disubstituted Cyclopropa[ c ]pyranosides from 2,3‐Epoxy‐4‐triflate‐pyranosides Reaction of benzyl 2,3‐anhydro‐4‐ O ‐trifluoromethylsulfonyl‐β‐ L ‐ribopyranoside ( 1 ) and benzyl 2,3‐anhydro‐4‐ O ‐trifluoromethylsulfonyl‐α‐ D ‐ribopyranoside ( 4 ) with malonic acid derivatives yields, via the carbanions, the cyclopropa‐monosaccharides 3 and 6 . The ester residues attached to the cyclopropane moiety can be saponified to give the corresponding acids which can be coupled to new carbohydrate amino acid derivatives of type 9 which are of biological interest in different immunological assays.