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Synthese von 6‐Methoxy‐2,5‐dimethyl‐2 H ‐isoindol‐4,7‐dion, einem Alkaloid aus Reniera ‐Arten
Author(s) -
SchubertZsilavecz Manfred,
Schramm Hans Wolfgang
Publication year - 1991
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1991199101168
Subject(s) - isoindole , chemistry , paraformaldehyde , stereochemistry , alkaloid , medicinal chemistry , organic chemistry
Synthesis of 6‐Methoxy‐2,5‐dimethyl‐2 H ‐isoindole‐4, 7 ‐dione, an Alkaloid from Reniera Species 6‐Methoxy‐2,5‐dimethyl‐2 H ‐isoindole‐4, 7 ‐dione ( 4 ) can easily be obtained in high yields in a one‐pot synthesis by heating sarcosine ( 2 ) and paraformaldehyde in the presence of 3‐methoxy‐2‐methyl‐1,4‐benzoquinone ( 1 ).