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Synthese des Thiophosphatidylcholins und seiner Analogen
Author(s) -
Młotkowska Barbara,
Markowska Anna
Publication year - 1991
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1991199101142
Subject(s) - chemistry , phosphonate , stereochemistry , nuclear magnetic resonance spectroscopy , sulfide , organic chemistry
Synthesis of Thiophophatidylcholine and Its Analogues Synthesis of thiophatidylcholine 5 , its phosphonothionate 7 and phosphonate 9 analogues are described. A novel facile rearrangement of 2‐(2,3‐distearoyloxypropylthio)‐1,3,2‐dioxaphospholane ( 3 ) into 2‐(2,3‐distearoyloxypropyl)‐1,3,2‐dioxaphospholane 2‐sulfide ( 6 ) was observed by 13 P‐NMR spectroscopy.