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Neopentylierung von Phenolen und Hydrochinonen
Author(s) -
Quast Helmut,
Schulze Johannes
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199019900197
Subject(s) - chemistry , hydroquinone , phenol , steric effects , ether , organic chemistry , medicinal chemistry
Abstract Neopentylation of phenol, the hydroquinones 6 as well as the hydroquinone diacetates 8 by means of neopentyl iodide in diethylene glycol dimethyl ether in the presence of cesium carbonate affords high yields of the neopentyl ethers 2a and 7 , respectively. Even sterically hindered hydroquinones and hydroquinone diacetates, e.g. 6e and 8c, d , are smoothly converted to the neopentyl ethers 7c – e .