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Steroids, XLII. Configurational analysis of 3‐methoxy‐16‐methylestra‐1,3,5(10)‐trien‐17‐ol derivatives
Author(s) -
Meskó Eszter,
Schneider Gyula,
Dombi György,
Zeigan Dieter
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199019900181
Subject(s) - chemistry , hydroxymethyl , stereochemistry , nmr spectra database , computational chemistry , two dimensional nuclear magnetic resonance spectroscopy , spectral line , medicinal chemistry , quantum mechanics , physics
The four possible isomers of 16‐hydroxymethyl‐3‐methoxyestra‐1,3,5(10)‐trien‐17‐ol 5a, 6a, 7a, 8a were converted into the corresponding 16‐methyl analogues 4a, 11a, 12a, 13a , which were characterized from their 1 H‐ and 13 C‐NMR spectra. The results permit a configurational correlation with 16‐methyl derivatives reported in the literature.