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Cycloadditionen, 18. 5‐Aminoisoxazole durch Cycloaddition von Nitriloxiden an Inamine
Author(s) -
Himbert Gerhard,
Kuhn Hildegard,
Barz Michael
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199019900177
Subject(s) - nitrile , cycloaddition , chemistry , azirine , medicinal chemistry , organic chemistry , catalysis , ring (chemistry)
Cycloadditions, 18. — 5‐Aminoisoxazoles by Cycloaddition of Nitrile Oxides to Ynamines Ten differently substituted ynamines 1a – j react with five nitrile oxides 3a – e to give the 5‐aminoisoxazoles 4a – z . The stannyl‐substituted ynamine 1c furnishes the same compounds (e.g. 4a – d ) by reaction with the hydroximoyl chlorides 2a – d . Two representatives of 4 – b and p ‐ can be transformed into the corresponding 1‐azirine‐3‐carboxamides 6a and b .