Premium
Novel, diastereoselective synthesis of 3‐amino‐1‐alkanols
Author(s) -
Oszbach György,
Neszmélyi András
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199019900138
Subject(s) - chemistry , benzaldehyde , ketone , nuclear magnetic resonance spectroscopy , stereochemistry , organic chemistry , catalysis
Benzaldehyde adds to 1‐pyrrolidinylcyclohexene under mild conditions giving the amino ketone 3a . The unstable ketone was reduced to the epimeric alcohols 4 and 5 , the stereochemistry of which was determined by 2D‐NMR correlation spectroscopy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom