Natural product chemistry, 140. Synthesis of some new acridones | Zendy

Reisch Johannes | Zendy; Herath H. M. T. Bandara | Zendy; Kumar N. Savitri | Zendy

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Natural product chemistry, 140. Synthesis of some new acridones

Author(s) -

Reisch Johannes,

Herath H. M. T. Bandara,

Kumar N. Savitri

Publication year - 1990

Publication title -

liebigs annalen der chemie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 0170-2041

DOI - 10.1002/jlac.1990199001189

Subject(s) - acridone , chemistry , methylenedioxy , stereochemistry , organic chemistry , alkoxy group , alkyl

Methyl 6‐amino‐2,3‐dimethoxybenzoate ( 6 ) which was obtained from 6‐formyl‐2,3‐dimethoxybenzoic acid ( 1 ), was treated with phloroglucinol to give two new acridone alkaloids, 1,3,8‐trihydroxy‐7‐methoxy‐9‐acridone ( 7 ) and 1,3‐dihydroxy‐7,8‐dimethoxy‐9‐acridone ( 8 ). Methylation of 7 and 8 gave another four new acridone alkaloids, 1,8‐dihydroxy‐3,7‐dimethoxy‐9‐acridone ( 9 ), 1,8‐dihydroxy‐3,7‐dimethoxy‐10‐methyl‐9‐acridone ( 10 ), 1‐hydroxy‐3,7,8‐trimethoxy‐10‐methyl‐9‐acridone ( 11 ) and 1,3,7,8‐tetramethoxy‐10‐methyl‐9‐acridone ( 12 ).

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