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Azole, 31. Stellvertretende nucleophile Substitution von Wasserstoff in Nitrobenzotriazol‐Derivaten
Author(s) -
Bernard Marek K.,
Szoja Cezary,
Wrzeciono Urszula
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1990199001142
Subject(s) - chemistry , carbanion , nitro , azole , nucleophilic substitution , nucleophile , medicinal chemistry , substitution reaction , substitution (logic) , stereochemistry , organic chemistry , catalysis , antifungal , medicine , alkyl , dermatology , computer science , programming language
Azoles, 31. — Vicarious Nucleophilic Substitution of Hydrogen in Nitrobenzotriazole Derivatives 4‐, 5‐, 6‐ and 7‐Nitrobenzotriazole derivatives 1a ‐ 1f , 4a and 4b react with carbanions of chloromethyl, bromomethyl, and α‐chloropropyl phenyl sulfones ( 2a ‐ 2c ) to give products of the vicarious nucleophilic substitution of hydrogen in ortho and para or exclusively in ortho position with respect to the nitro group. The structures of the products have been determined by means of 1 H‐NMR spectroscopy. On treating with 2c , 1e gives the unexcepted compound 6 .