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Synthese enantiomerenreiner γ‐Keto‐δ‐aminosäuren, zentrale Bausteine vieler Enzyminhibitoren
Author(s) -
Radunz HansEckart,
Reißig HansUlrich,
Schneider Günther,
Riethmüller Angelika
Publication year - 1990
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1990199001133
Subject(s) - chemistry , enantioselective synthesis , amino acid , stereochemistry , enzyme , combinatorial chemistry , organic chemistry , catalysis , biochemistry
Synthesis of Enantiomerically Pure γ‐Keto‐δ‐amino Acids, Central Building Blocks of Enzyme Inhibitors An enantioselective and efficient synthesis of γ‐keto‐δ‐amino acids as building blocks for certain enzyme inhibitors is presented. These compounds are also attractive for syntheses of homostatine derivatives.