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Notizen / Notes Polyazanaphthalenes, I The Reaction of Ethyl 6‐Amino‐5‐cyano‐4‐aryl‐2‐methyl‐4 H ‐pyran‐3‐carboxylate with Nucleophilic Reagents
Author(s) -
Harb AbdelFattah A.,
Hesien AbdelHaleem M.,
Metwally Saoud A.,
Elnagdi Mohamed Hilmy
Publication year - 1989
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.1989198901102
Subject(s) - malononitrile , chemistry , hydrazine (antidepressant) , acetic anhydride , cyanoacetamide , pyridine , pyran , reagent , hydrate , organic chemistry , pyrazole , nucleophile , aryl , medicinal chemistry , catalysis , alkyl , chromatography
Ethyl 6‐amino‐5‐cyano‐4‐aryl‐2‐methyl‐4 H ‐pyran‐3‐carboxylates 4 could be converted into 1,6‐diazanaphthalene, pyrano‐[2,3‐ c ]pyrazole, isoxazolo[3,4‐ b ]pyridine, pyrano[2,3‐ b ]pyridine, 1,8‐diazanaphthalene, and pyrano[2,3‐ d ]pyridine derivatives on treatment with malononitrile, hydrazine hydrate, hydroxylamine hydrochloride, (arylmethylene)malononitrile, cyanoacetamide, and acetic anhydride, respectively.