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Eine effiziente und stereoselektive Synthese von D ‐ erythro ‐Sphingosin
Author(s) -
Radunz HansEckart,
Devant Ralf M.,
Eiermann Volker
Publication year - 1988
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198819881117
Subject(s) - stereoselectivity , chemistry , diastereomer , sphingosine , stereochemistry , yield (engineering) , derivative (finance) , nucleophile , organic chemistry , catalysis , biochemistry , physics , receptor , financial economics , economics , thermodynamics
An Efficient and Stereoselective Synthesis of D ‐ erythro ‐Sphingosine A highly stereoselective 3‐step synthesis, leading in 81% overall yield to D ‐ erythro ‐sphingosine ( 8 ), is described. Several further examples for the nucleophilic addition to the serinal derivative 1 are given.