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Reaktion von elektronenreichen Heterocyclen mit Orthocarbonsäure‐Derivaten, 12. Formylierung von Vinylindolen mit Diethoxycarbenium‐tetrafluoroborat
Author(s) -
Flo Camran,
Pindur Ulf
Publication year - 1988
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198819880921
Subject(s) - chemistry , formylation , tetrafluoroborate , medicinal chemistry , organic chemistry , catalysis , ionic liquid
Reactions of Electron‐Rich Heterocycles with Orthocarboxylic Acid Derivatives, 12. – Formylation of Vinylindoles with Diethoxycarbenium Tetrafluoroborate 2‐ and 3‐vinylindoles 1, 3 are formylated with diethoxycarbenium tetrafluoroborate regioselectively. The significant selectivity and reactivity of formylation of diethoxycarbenium ion in comparison with other thermodynamically more stable dialkoxycarbenium ions are compatible with the known results of hetaryl functionalisation with orthocarboxylic acid derivatives.