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Racemic and enantiomeric all‐trans ‐fecapentaene‐12 and ‐14
Author(s) -
Pfaendler Hans Rudolf,
Maier Franz Karl,
Klar Sonja,
Göggelmann Waltraud
Publication year - 1988
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198819880514
Subject(s) - chemistry , enantiomer , stereochemistry , ames test , salmonella , biology , bacteria , genetics
The syntheses of the following crystalline all‐trans compounds are described: (±)‐fecapentaene‐12 ( 1a ), natural (S)‐(+)‐fecapentaene‐12, unnatural ( R )‐(–)‐fecapentaene‐12, (±)‐fecapentaene‐14 ( 1b ), and ( S )‐(+)‐fecapentaene‐14. Both enantiomers and the racemate of fecapentaene‐12 induce comparably strong mutagenic effects in the Ames assay.